Network NBC
Original Air Date 1969-1976
67

After a few Pink Panther films had hit the big screen in the '60s, America was treated to a cartoon showcase based on some of the themes and characters from the Blake Edwards/Peter Sellers franchise. The Pink Panther Show featured the bumbling adventures of a cartoon Inspector Clouseau and his "peanut butter and garlic sandwich"-loving Spanish sidekick Deux Deux; a Jackie Mason inspired aardvark trying to catch a sly red ant; an actual Pink Panther who lives only to infuriate his mustachioed next door neighbor; and a slew of other stories. All of the little cartoon-ettes were accompanied by the sizzling Henri Mancini jazz score from the famed movies. It was a cool collection of animation that ranged from slapstick to surreal, and gave us some wonderful characters to cherish. And let's not forget the most important part: Even though all of these animated nuggets were only loosely tied to the films, they were still exponentially better than the Steve Martin remake.

List Continues in descending order below
Network CBS
Original Air Date 1970-1972
100

The success of the animated Archie Show was big, as it extended into music with The Archies hit song "Sugar, Sugar." This led to another Archie Comic coming to television with Josie and the Pussycats, which took pre-existing Archie Comics universe character Josie and put her into a new scenario as she formed a band -- the comic book character also reflected the change, in a bit of synergy. Hanna-Barbera produced Josieand it's an amusing show for how it so specifically combined elements from the success of The Archie Show and Hanna-Barbera's own Scooby-Doo, as Josie and her friends not only played music together, but inadvertently stumbled into mysteries they would ultimately help solve.

Despite only running for 16 episodes (not counting the amusing spin-off/continuation Josie and the Pussycats in Outer Space), frequent repeats, the spunky characters and a great theme song kept Josie in the public consciousness for years to come, ultimately leading to an underrated film version in 2001.

Network Syndicated
Original Air Date 1985-1986
99

One of the more popular cartoon/toy marketing machines of the Eighties was M.A.S.K., the Mobile Armored Strike Kommand (yes, command with a 'K', that's what happens when you have to make an acronym fit into your story concept). The show was a weird kind of G.I. Joe-Transformers hybrid, but it managed to combine the best elements of those franchises while adopting few of their flaws. But what really set it apart was the namesake of the show -- the super-powered masks the characters wore. The masks provided the ethnically-diverse-yet-stereotypical cast with abilities like anti-gravity, flight, and energy beams.

Matt Trakker was the ruggedly handsome, rich, charismatic lead of the show. His pimp ride was a red Chevrolet Camaro G3 that transformed into a gull-winged fighter plane. His son Scott and his friend/pet robot T-Bob provided some comic relief. And since Scott was always upgrading his expensive buddy, he provided plenty of validation for the little boys who would grow up to be today's tech geeks and robot nerds. But one of the more notable aspects of the show was the fact that it showed a single dad taking care of his only son while fighting the forces of evil.

Network ABC
Original Air Date 2000
98

In some ways this is the Firefly of animated series -- aired out of order and then quickly discarded by a network that didn't feel it fit with their programming. Only six episodes were produced, and only two of them aired, but there was a lot of very funny material in Kevin Smith's adaptation of his own film. A rather brilliant second episode parodied that old television staple, with the characters trapped together, reminiscing on past events -- only here, with only one episode having been produced, all of their memories are of that previous week's events... before things get really hysterical and surreal. Starring the entire main cast of the Clerks films, not to mention Alec Baldwin as the Lex Luthorish Leonardo Leonardo, Clerks was able to do a lot more broad comedy and parodies than the films, with episodes evoking everything from Fast Times at Ridgemont High to the unfortunate results of a Transformer transforming with a person inside him.

Network NBC
Original Air Date 1981-1990
97

Like many of the shows represented on our Top 100, The Smurfs is a cartoon we here at IGN grew up with, and as such it holds a special place in our memories. Based on a Belgian comic strip, the tiny blue-skinned Smurfs became an unstoppable media empire with this popular 1980s Hanna-Barbera animated series. The animation itself wasn't much to speak of, but the stories told over the course of its 256 episodes were kiddie cocaine to those of us who grew up in the '80s. The peaceful Smurfs, led by Papa Smurf and predominantly male (with the sole exception of Smurfette), were often chased by the evil wizard Gargamel and his cat Azrael.

Watching the series as an adult, one can't help but sympathize a little bit with the Smurf-hating Gargamel -- the constantly upbeat and overly saccharine attitudes of most of the Smurfs, mixed with whininess and an extreme overuse of the word "smurf" by everyone, makes you start to root for the poor, bumbling wizard who just wants to make some nice Smurf stew.

Network NBC
Original Air Date 1973-1974
96

Lots of live-action TV series have gotten cartoons over the years -- Gilligan's Island, Happy Days, even The Dukes of Hazzard! -- but rarely have such hand-drawn variations been so successful in conveying the spirit of their forbearers. Running for two seasons (from 1973 to 1974) on NBC, these Star Trek half-hour adventures are seen by many fans as the lost fourth year of Captain Kirk and crew's legendary five-year mission. Featuring animation by Filmation, the show didn't typically excel visually -- cartoons proved to most definitely not be the final frontier for the Enterprise. But the world of animation did offer the Star Trek writers the chance to portray things they could never do on a live-action budget at the time -- from three-armed crew members to new and exciting alien worlds. Most importantly, many of the writers of the original show returned here, from D. C. Fontana to Samuel A. Peeples to Gene Roddenberry himself. That fidelity to the 1960s show, plus the inclusion of William Shatner, Leonard Nimoy, and most of the other actors (or their voices anyway), led to Star Trek: The Animated Series becoming one of the most interesting, if under-viewed, shows in all of the Trekfranchise.

Network Cartoon Network
Original Air Date 2004-2006
95

Although it's mostly an upbeat story with amazing action scenes, Fullmetal Alchemistscores big points for touching on many aspects of the human condition. The main characters are the Elric brothers, Ed and Al. Ed is the famous Fullmetal Alchemist who almost lost his little brother Al in an accident that occurred when the boys tried to resurrect their dead mother using alchemy. Edward managed to contain his brother's soul in a suit of armor. While he did manage to save his brother's life, he had to pay a great price himself. To get back what they lost, the brothers embark on a journey to find the legendary Philosopher's Stone.

This story doesn't pull any punches. Right from the first few episodes we're presented with the topics of death, lost hope, and betrayal. The real emotional engine of the series is the relationship between Ed and Al, as the two boys go through turmoil that no one of any age should have to deal with. By the end of this series you just want to give them both a hug and tell them everything will be okay. FMA is one of those special anime that became more than a mere animated show; it was a powerful weekly drama.

Network Cartoon Network
Original Air Date 2005-Present
94

Based on the comic strip of the same name by African American cartoonist Aaron McGruder, The Boondocks takes a sharp satirical look at American society, with an emphasis on black culture and race relations, from hip-hop and movies to icons like Martin Luther King, Jr. and Oprah Winfrey. Controversial from the start, The Boondockshas drawn criticism for its use of the N-word and for its portrayal of such historical figures as King.

The series follows the Freeman family -- 10-year-old Huey, his eight-year-old brother Riley and their grandad Robert -- and their experiences after the boys moved from the South Side of Chicago to live with Grandad in the suburbs. The two seasons produced so far have been released on DVD, uncensored and complete with two previously unaired episodes from season two, which were highly critical of BET (which makes for some amusing episode commentaries by McGruder and the cast).

Network Syndicated
Original Air Date 1991-1992
93

Disney Afternoon's response to Batman, but with a duck looking more The Shadow than The Dark Knight, is one of the many reasons why after-school cartoons rule. This DuckTales spin-off ran from 1991 to 1995, and during that time the goofy yet thrilling adventures of Drake Mallard never ceased to satisfy. And how could they not: awesome sidekick who was more Han Solo than Dick Grayson? Check, his name's Launchpad and he's about 10 different types of cool. Duck-themed aerial transport? Check. A few homages to Frank Miller's The Dark Knight Returns? Some nods to James Bond and Marvel for good measure? Double-check. And that theme song makes for a geeky-cool ringtone, which is nice. From DW's misadventures with Gizmoduck to some throw-downs with villain Flintheart Glomgold, our time in the city of St. Canard was more than worthwhile. It was pure fun.

Network Nickelodeon
Original Air Date 1991-1994 & 1996-2004
92

Want to know what kids are thinking? Well yer gonna. Rugrats might have had a sort of hideous animation style that transformed a bunch of toddlers into grotesque monstrosities, but it sure was popular. Sure, there were grownups around to let us know exactly what was going on, but the focus of the show was "how kids look at things." How they could see monsters and magic in everyday occurrences simply because they don't understand the world yet. With all the toddlers able to effectively communicate with each other through baby speak, Rugrats took its cues from earlier shows like Muppet Babies and had the kids use their imaginations to create adventures for themselves. The misadventures of Tommy, Chuckie, Phil and Lil, and even Tommy's devilish cousin Angelica ran for 13 years! And not only that, the characters have a new show called All Grown Up, where you can find them...all grown up and in middle school.

Network Cartoon Network
Original Air Date 2000-2007
91

On the heels of the success of Space Ghost Coast to Coast, Cartoon Network's Adult Swim launched several series using previously created animated characters in offbeat and bizarre new situations. Harvey Birdman was an especially clever example of this type of show, reimagining the 1960s superhero as a lawyer. A wonderful conceit of the series had Harvey's cases involving other classic cartoon characters, but with many adult scenarios thrown in -- including Scooby and Shaggy arrested for possession, Fred Flintstone turned mafia don, Boo Boo accused of terrorism, and Super Friends's Apache Chief suing after spilled coffee on his lap prevents him from, ahem, "growing larger." Able to make use of these actual characters, and sometimes clips from the shows we know them from, Harvey Birdman worked as both a parody and homage to these animated characters we know and love, with plenty of funny, surreal jokes along the way.

Network Spike TV
Original Air Date 2007-Present
90

As one of the few currently running cartoons on the list, Afro Samurai has made a quick and indelible impression on us here at IGN. Based on a manga created by Takashi Okazaki, this anime series mixes plenty of top-tier voice talent (including Samuel L. Jackson, Kelly Hu, and Ron Perlman, just to name a few) with an excellent soundtrack (provided by the Wu-Tang Clan's RZA) and a budget large enough to ensure the very best quality from every aspect of the show.

The story is a simple one: As a child Afro watches his father die at the hands of an evil gunman, only to spend the rest of his life training in the samurai way to take down his father's killer and become "Number One." Filled with the over-the-top violence and gore that you would expect from a mature action anime series, Afro Samurai added a quirky story with equally as quirky characters to make a series that we couldn't help but enjoy.